Stress ossidativo che porta al clivaggio della prl con conseguente formazione di una molecola che stimola langiogenesi e frammenti con attivita proapoptotica. Our reputation ensures you are recognised for your skills and talent no matter where in the world you choose to pursue your dreams. Peripartum cardiomyopathy occurs globally and is not a. Kardiomiopati peripartum menjadi penyebab meningkatnya selengkapnya. Additionally, 2% of patients had severely deteriorated left. This consensus document is an outstanding resource for stateoftheart knowledge of peripartum cardiomyopathy.
Patogenesis kardiomiopati dilatasi remodeling jantung respon kompensasi maladaptasi terhadap disfungsi kontraksi dan peningkatan volume ventrikel kiri elongasi kardiomiosit dikontribusi oleh aktivasi neurohormonal aktivasi simpatis peningkatan aktivasi simpatis mekanisme kompensasi down regulation dari reseptor. Ppcm primarily affects women over 30 years old who have multiparity and gestational hypertension. Anuja and richa pregnancy outcome in peripartum cardiomyopathy in the study 911 women were multiparous, the ejection fraction was in the range of 2944 %, one case had ef of 45%, 511 women developed arrhythmia, there were 3 maternal deaths 2 being postnatal and 1 antenatal multiparous women who died of congestive heart failure. Prevalensi preeklampsi berkisar antara 210% kehamilan sedangkan prevalensi terjadinya kardiomiopati peripartum sekitar 1. Ppcm is still regarded as a disease of unknown aetiology, although recent evidence suggests a role for a 16 kda prolactin derivative produced by. Etiologi dan patofisiologi kardiomiopati dilatasi kardiomiopati dilatasi atau dilated cardiomyopathy dcm adalah gangguan miokard yang didefinisikan oleh dilatasi dan gangguan fungsi sistolik ventrikel kiri, atau kedua ventrikel, tanpa adanya penyakit arteri koroner, kelainan katup, atau penyakit perikard. Ppcm is still regarded as a disease of unknown aetiology, although recent evidence suggests a role for a 16 kda prolactin. Berikut ini adalah download jurnal gratis yang merupakan kumpulan file dari berbagi sumber tentang kardiomiopati adalah pdf yang bisa bapakibu gunakan dan diunduh secara gratis dengan menekan tombol download biru dibawah ini. Dalam refarat ini penulis membahas tentang kardiomiopati dan dan berbagai macam hal yang berhubungan dengan kardiomiopati. Department of obstetrics and gynaecology, sree balaji medical college and hospital, bharath university, chrompet, chennai, india.
Peripartum cardiomyopathy is idiopathic heart failure occurring in the absence of any determinable heart disease during the last month of pregnancy or the first 5. Kardiomiopati peripartum ppcm merupakan suatu keadaan kardiomiopati. Puji syukur kepada tuhan yang maha esa karena atas berkatnya penulis dapat menyelesaikan tugas refarat ini. Pearson gd, veille jc, rahimtoola s, et al peripartum cardiomyopathy. Peripartum cardiomyopathy is defined as a nonfamilial form of peripartum heart failure characterized as an idiopathic cardiomyopathy presenting with heart failure secondary to leftventricular lv systolic dysfunction towards the end of pregnancy or in the months following delivery, where no other cause of heart failure is found as. Spirito hospital, rome, 2cnr clinical physiology institute, asstgreat metropolitan hospital niguarda, milan, italy abstract. Most pregnant women who died after myocardial infarction did so at the time of initial infarction, and maternal mortality was greatest if the infarction was late in pregnancy. Its aim is to improve quality of life and longevity. Kardiomiopati peripartum didefinisikan sebagai disfungsi ventrikel kiri yang mengarah ke gagal jantung, tanpa diketahui penyebabnya serta terjadi pada bulan terakhir kehamilan hingga 5 bulan postpartum. Peripartum cardiomyopathy ppcm is a pregnancyassociated myocardial disease with marked left ventricular systolic dysfunction.
Background ppcm is a significant cause of maternal and. Multigravida 36 weeks of pregnancy with gemeli and peripartum. Diagnosis dan penatalaksanaan pada kardiomiopati peripartum definisi. Dexametason 2x10 mg, nifedipin 10 mg6 jam, mgso 4 sesuai protap, serta terminasi kehamilan dengan section caesaria. Peripartum postpartum cardiomyopathy ppcm is the most common cardiomyopathy in pregnancy. Berikut ini adalah download jurnal gratis yang merupakan kumpulan file dari berbagi sumber tentang jurnal kardiomiopati pdf yang bisa bapakibu gunakan dan diunduh secara gratis dengan menekan tombol download biru dibawah ini. Background ppcm is a significant cause of maternal and infant morbidity and mortality. Ppcm may be difficult to diagnose because symptoms of heart failure can mimic those of pregnancy. The cause of ppcm has remained elusive until recently. A cardiac emergency for pregnant women, she gently explains in lay terms the symptoms, treatments, risk levels, and warning signs of this illness as well as the different types of medical tests that can help save your life and your heart. Current state of knowledge on aetiology, diagnosis, management, and therapy of peripartum cardiomyopathy.
Doc lp kardiomiopati peripartum laily lely academia. Secondary analyses included evaluation of the prevalence of hypertensive disorders, multiple gestations, and multiparity. Although initially described in 1849 2, it was not recognized as a distinct clinical entity until the 1930s 3. Peripartum cardiomyopathy is a rare, serious disease of late pregnancy or early puerperium. It typically develops during the last month of, and up to 6 months after, pregnancy in women without known. Peripartum cardiomyopathy ppcm is a form of dilated cardiomyopathy of unclear etiology affecting women without preexisting heart disease during the last month of pregnancy or during the first 5 months postpartum. Its incidence shows marked geographic and ethnic variation, being most common in africa and among women of african descent.
Peripartum cardiomyopathy ppcm is defined as the development of cardiac failure between the last month of pregnancy and 5 months postpartum, the absence of an identifiable cause, the absence of recognizable heart disease prior to the last month of pregnancy, and left ventricular systolic dysfunction demonstrated by classic echocardiographic. Fett jd, carraway rd, dowell dl, king me, pierre r. Tidak adanya gelombang a termasuk atrial fibrilasi 6. It is characterized by left ventricular dysfunction and symptoms of heart failure that can arise in the last trimester of pregnancy or up to 5 months after delivery. Jumlah penderita kardiomiopati peripartum yang dirawat di rumah sakit santo antonius dari 20082012 sejumlah 40 orang dengan distribusi frekuensi umur 20 29. Peripartum cardiomyopathy in the hospital albert schweitzer district of haiti. Dec 28, 2012 peripartum cardiomyopathy ppcm is a form of dilated cardiomyopathy of unclear etiology affecting women without preexisting heart disease during the last month of pregnancy or during the first 5 months postpartum. Peripartum cardiomyopathy in an elderly patient with in. Multigravida 36 weeks of pregnancy with gemeli and. The relationship between preeclampsia and peripartum. Peripartum cardiomyopathy ppcm is a form of dilated cardiomyopathy that is defined as a deterioration in cardiac function presenting typically between the last month of pregnancy and up to six months postpartum. Pasien di diagnosis dengan g 2 p 1 a 0 usia kehamilan 36 minggu, janin gemeli hidup intrauterine presentasi kepala dengan peripartum kardiomiopati. Peripartum cardiomyopathy a case report biomedical and.
Peripartum cardiomyopathy, pregnancy, heart failure disease name and synonyms peripartum cardiomyopathy cardiomyopathy in pregnancy definition the peripartum cardiomyopathy ppcm is classified as a specific cardiomyopathy that develops in the last period of pregnancy or in the first period of puerperium 1,2. Clinical characteristics of patients from the worldwide registry on peripartum cardiomyopathy ppcm. Peripartum cardiomyopathy ppcm is the unexplained loss of maternal cardiac systolic function in the period surrounding parturition. Predictors of prognosis in patients with peripartum. Price new from used from paperback, may 23, 2011 please retry. Incidence and outcome of peripartum cardiomyopathy from a tertiary hospital in south india. In 1971, demakis and colleagues 1 first defined peripartum cardiomyopathy as idiopathic heart failure hf occurring in the absence of any determinable heart disease in the last month of pregnancy or during the first 5 months postpartum. Peripartum cardiomyopathy is a potentially lifethreatening pregnancyassociated disease that typically arises in the peripartum period and is marked by left ventricular dysfunction and heart failu. As more and more women at increasing age go for assisted. Diagnosis requires symptoms of heart failure in the last month of pregnancy or within five months of delivery in the.
Although initially described in 1849, it was not recognized as a distinct clinical entity until the 1930s. Doctor barbara maria colombo1 and dr simone ferrero2 creation date. Professor paola melacini 1department of internal medicine, san martino hospital, university of genoa, italy. Kardiomiopati peripartum didefinisikan sebagai disfungsi ventrikel kiri yang mengarah ke gagal jantung, tanpa diketahui penyebabnya serta. Peripartum cardiomyopathy ppcm is a rare and potentially fatal disease which presents with symptoms of heart failure primarily due to left ventricular lv systolic dysfunction in the last month of pregnancy and up to 56 months after delivery. Peripartum cardiomyopathy ppcm american heart association. Ppcm is defined as an idiopathic cardiomyopathy that presents with heart failure secondary to left ventricular lv systolic dysfunction toward the end of pregnancy or in the months after delivery, in the absence of any other cause of heart failure. As with other forms of dilated cardiomyopathy, ppcm involves systolic dysfunction of the heart with a decrease of the left ventricular ejection fraction ef with. Peripartum cardiomyopathy as a diagnosis needs to be considered in antenatal and immediate postpartum women with clinical features of cardiac failure. Abstractperipartum cardiomyopathy is a lifethreatening condition of unknown cause that occurs in previously healthy women during the peripartum period. Peripartum cardiomyopathy ppcm is a rare heart disease which affects previously healthy women toward the end of.
Increasing cardiovascular stresses of late pregnancy, especially when intensified by parturition, seriously compromise women with ischemic heart disease. The heart failure association hfa is a registered branch of the esc. Peripartum cardiomyopathy ppcm is an uncommon disorder associated with pregnancy in which the heart dilates and weakens, leading to symptoms of heart failure. Jurnal kedokteran dan kesehatan indonesia journal uii. Peripartum cardiomyopathy in an elderly patient with invitro. Diagnosis requires symptoms of heart failure in the last month of pregnancy or within five months of delivery in.
In her book, peripartum and postpartum cardiomyopathy. Penurunan y yang cepat termasuk perikarditis konstriktif dan kardiomiopati restriktif 5. Peripartum cardiomyopathy ppcm, also called pregnancyassociated cardiomyopathy is a rare cause of heart failure hf that affects women late in pregnancy or in the early puerperium. Peripartum cardiomyopathy ppcm, also known as postpartum cardiomyopathy, is an uncommon form of heart failure that happens during the last month of pregnancy or up to five months after giving birth. Peripartum cardiomyopathy characteristics and outcome in a tertiary care hospital. Prevalence and outcome of peripartum cardiomyopathy in.
Cardiomiopatia peripartum eziopatogenesi non nota, ruolo di infezioni, infiammazione, sistema immunitario. Kardiomiopati dilatasi kd dilated cardiomiopathy dcm mempunyai karakteristik peningkatan volume sistolik dan diastolik ventrikel kiri yang ditandai dengan terdilatasinya kedua ventrikel terutama ventrikel yang kiri, jarang yang kanan, yang berakibat menurunnya kontraktilitas miokardium sehingga menurunkan curah jantung. Although this condition can lead to major complications, including severe heart failure, arrhythmias, thromboembolic events, and death, the majority of women with this condition demonstrate a complete or partial recovery. Peripartum cardiomyopathy ppcm is a dilated cardiomyopathy defined as systolic cardiac heart failure in the last month of pregnancy or within five months of delivery. Peripartum cardiomyopathy in an elderly patient with invitro fertilization pregnancy pranay shah, asit bhagwati, anu adlakha. Dengan adanya refarat ini, penulis berharap dapat menambah pengetahuan pembaca tentang kardiomiopati. Peripartum cardiomyopathy ppcm is a rare but potentially lethal complication of pregnancy occurring in approximately 1. Kardiomiopati dilatasi informasi kedokteran dan kesehatan. Ppcm, which affects thousands of women each year in the us, was first described in the 1800s, yet its. Diagnosis dan penatalaksanaan pada kardiomiopati peripartum. Ppcm is a dilated form of the condition, which means the heart chambers enlarge and the.
Diagnosis of ppcm is based on symptoms and signs of heart failure during pregnancy or in postpartum period with echocardiography. Kardiomiopati peripartum ppcm adalah penyakit yang ditandai dengan pembesaran dinding otot jantung. Ppcm, which affects thousands of women each year in the us, was first described in the 1800s, yet its etiology is still unclear. Multigravida hamil 36 minggu dengan gemeli dan peripartum. Peripartum cardiomyopathy is a rare form of idiopathic dilated cardiomyopathy with left ventricular systolic dysfunction that can result in signs and symptoms of heart failure. Peripartum cardiomyopathy ppcm is a cause of pregnancyassociated heart failure. Ppcm is fraught with controversies in its definition, epidemiology, pathophysiology, diagnosis and management. Patients with peripartum dilated cardiomyopathy will experience symptoms and signs. Peripartum and postpartum cadiomyopathy paperback may 23, 2011 by anner t porter author see all formats and editions hide other formats and editions.
Risk of subsequent pregnancy in women with a history of. Kardiomiopati peripartum ppcm adalah bentuk kegagalan jantung yang terjadi pada wanita hamil terutama dalam beberapa. Ppcm affects women worldwide and is a leading cause of maternal mortality. Different characteristics of peripartum cardiomyopathy. Warraich et al, 20 in a study from south africa, mozambique, and haiti, found that the frequencies and reactivities of immunoglobulins were similar in distribution in patients with peripartum cardiomyopathy, irrespective of the geographic location. Peripartum cardiomyopathy ppcm is a rare heart disease which affects previously healthy women toward the end of pregnancy or in the months.
59 788 733 1038 1688 272 709 188 820 1054 951 1340 1065 1422 89 543 1406 1505 593 1457 872 555 248 1632 1667 971 1313 156 444 281 1240 1004 860 870 253 763 1476 706 1012